Inducing experimental asthma in rats by introducing the substance – Ovalbumin (the main avian blood protein) triggered inflammation in the bronchi, with cytokine levels in the blood rising accordingly. CBD treatment lowered the release of cytokines and their blood level decreased. CBD has been found to have medical potential to calm the inflammatory response to asthma. Besides suppressing inflammation, CBD inhibits mucus production thus reducing airway obstruction and preventing the worsening of asthma in humans. Cytokine IL-13 is the cytokine that causes increased mucus production in the airways. A recent study found that CBD lowers levels of this cytokine in the airways, protects the lung tissue from infections, and thus treats and assists in respiratory diseases and asthma.

T cells penetrate the respiratory system and produce cytokines in response to asthmatic stimulation. CBD suppresses the T-cell reaction and inhibits the release of cytokines. A 1999 study (Waksman, Y. et al) found that the cytokine tumour necrosis factor – TNF plays an important role in creating inflammation and increasing the severity of asthma. CBD lowers the cytokine TNF level and thus helps calm inflammation.

It turns out in recent studies that the induction of asthma in animals has caused an increase in anandamide levels in the fluid of the airways. the higher level of anandamide decreased asthma severity.

CBD raises anandamide levels as a result of the inhibition of the FAAH enzyme that breaks down anandamide, thus helping anandamide in the respiratory vessels and soothe asthma. By these results, treating asthma using CBD oil is a promising and potentially great option for the near future.

Read in-depth about CBD as a Natural Treatment for Asthma:

• Cannabidiol reduces airway inflammation and fibrosis in experimental allergic asthma

• Allergen challenge increases anandamide in the bronchoalveolar fluid of patients with allergic asthma

• Activation of cannabinoid receptors prevents antigen-induced asthma-like reaction in guinea pigs

• Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways

• Evaluation of Serum Cytokines Levels and the Role of Cannabidiol Treatment in Animal Model of Asthma

Chronic Obstructive Pulmonary Disease

A disease that creates a restriction on the airflow that is not completely reversible. The disease is characterized by an advanced course and at the same time exacerbation.

The characteristic clinic includes shortness of breath in tan effort and chronic cough. Smoking is the most significant risk factor. The main treatment for exacerbating the disease includes oxygen supply, bronchiole expanders, and systemic steroids (liquid or powdery spray). Patients who suffer moderate or severe worsening add antibiotic treatment. Quitting smoking reduces the mortality rate and the risk of further worsening significantly.

Risk factors: Smoking – stopping smoking should be encouraged at all times. indoors (cooking oil, heating in an unventilated room) and outside the home, and occupational air pollution (dust and chemicals).

Prenatal factors: Any factor that affects the maturation of the lungs until birth and during childhood (low birth weight, pulmonary infections, etc..) increases the risk of having the disease later in life.

CBD as a treatment for Chronic Obstructive Pulmonary Disease [COPD]

During decades of research in the field of medical cannabis, researchers pointed to the effectiveness of cannabis in treating diseases and symptoms associated with lung diseases and respiratory tracts. All the results from individual studies conducted, and anecdotal reports showed that lowering inflammation helps chronic bronchitis patients, even though the way of consumption was in smoking. Activation of the CB1 and CB2 receptors by THC showed a reduction in respiratory inflammation.

Animal research summarized the findings and determined that CBD has great potential as an anti-inflammatory drug and improves lung function. Another study found that CBD has a positive effect after acute lung injury, especially in preventing subsequent infections.

CBD as a natural treatment for Bronchitis

CBD can reduce bronchitis and other chronic obstructive pulmonary diseases by expanding the airways, lowering resistance in the alveoli, and increasing the air current to the bronchial tubes. Another study found that activating CB1 receptors in the lungs prevents contractions of the smooth muscle that surrounds the air vessels of the lungs and also helps to expand the air ducts.

CBD as a natural treatment for respiratory diseases

Infections are the most common form of expression of many respiratory and lung diseases. CBD treatment during an ongoing inflammatory process in the body has great anti-inflammatory potential. All previous studies in animals and lung tissues in the laboratory showed a clear withdrawal of inflammation due to CBD treatment and thus opened the way for further current research in humans.

Recently, CBD’s antibiotic action has been re-examined and it has become clear that it has strong antibiotic activity and thus prevents the development of disease factors. In the past, the only way to consume cannabinoids was by smoking. The vast majority of doctors vigorously opposed this method of consumption. Today, hemp extractions and a variety of products taken by swallowing and absorbed under the tongue make CBD a natural and safe treatment for respiratory tract infections.

• Antibacterial activity of delta9-tetrahydrocannabinol and cannabidiol

• Antibacterial cannabinoids from Cannabis sativa: A structure-activity study

What is now known in the Study:

Shortly, In asthma patients, the airways are extremely sensitive to various stimuli, causing allergies that stimulate and worsen bronchial health. These stimuli can be smoke, cold air, or physical exercise. As a result of exposure to these irritating substances, immune cells, found in the walls of the airways, release substances that encourage inflammation and substances that cause smooth muscle contraction in the wall of the air ducts. A sudden and strong contraction of the muscle in the wall of the air ducts is what leads to acute shortness of breath.

Symptoms include:

• Wheezing in the breath

• Bouts of coughing and shortness of breath

• Chest pain

• Nocturnal cough

About 10% of the world’s population suffers from bronchial diseases. Asthma is a disease that causes considerable suffering and a significant reduction in the quality of life, if not diagnosed and treated properly. The diagnosis and evaluation of the severity of the bronchial disease consist of a clinical and laboratory diagnosis that relies on on and uses lung function and diagnosis of the allergic condition. The current treatment includes reducing exposure to aggravating factors, medication, and immuno-modulators treatment.

Other Lung Diseases that CBD treatment can be useful for:

Pneumonia is a lung infection that can cause very severe disease. The inflammation manifests itself in coughing, fever, and difficulty breathing. In many cases, it seems that pneumonia is generated as a result of the complication of another respiratory disease, such as the flu. Pneumonia can be treated at home with some antibiotics. It usually passes two or three weeks later. However, among older people and infants, the disease can be very serious and even fatal. In more severe cases, patients tend to be hospitalized until the infection passes and provided oxygen to facilitate breathing. For those patients in the risk group for severe pneumonia, a vaccine against the main bacterial infection factor, Pneumococci is offered.

Pneumococci are a type of streptococcus bacteria. The bacteria spread through contact with people who are ill or by healthy people who carry the bacteria in the back of their nose. Pneumococcal infections can be mild or severe.

Upper Respiratory Tract Infection

A disease is commonly called “colds”. The airways include the following organs: nose, pharynx, throat, trachea, and healthy bronchial. Inflammation of the upper airways is very common, and it is one of the most common reasons to visit a doctor of all ages. In most cases it is an infection caused by viruses and manifested in the following symptoms: Nasal congestion, excessive secretion of the mucous membranes of the airways (e.g. runny nose and phlegm), sneeze, cough, and sore throat. However, upper respiratory tract infection can be an allergic reaction and not necessarily due to infection.

Respiratory congestion may be accompanied by inflammation in the conjunctivitis of the eyes, sore throat, hushes, and cough. Clogged ears, facial pain, feeling of congestion in the area of the forehead or cheeks, and sometimes headaches. In the case of influenza, which is a unique disease of the upper airways, usually not only do the usual symptoms – such as runny nose, sore throat, and cough – appear, but also high fever, general bad feeling, and muscle pain throughout the body.

Chronic Bronchitis

Bronchioles are the tubes that transport air to the lungs. These tubes are covered on the inside with a thin layer of cells known as mucous membranes. When there is an inflammation it causes edema and secretion of a lot of phlegm. Viruses are the main generator of acute bronchitis. On the other hand, the cause of chronic bronchitis is contaminants that are in the air and that are inhaled into the lungs. The main cause of chronic brothel inflammation is cigarette smoke, but also severe air pollution or continuous exposure to dust can cause this inflammation. An allergic reaction is another possible cause of chronic bronchitis. Symptoms of bronchitis (acute or chronic) are coughing, phlegm emissions, weakness, fever, and sometimes chest discomfort – especially after coughing. Inflammation is defined as chronic when symptoms persist for at least three months each year for two years in a row.

Read more about CBD and treatment for inflammatory lung diseases:

The role of cannabinoids in inflammatory modulation of allergic respiratory disorders, inflammatory pain, and ischemic stroke.

Could Cannabis Help People With Lung Diseases?