Is CBD For Everyone?
Cannabidiol (CBD) is a molecule with a high level of pharmacological safety:
It does not cause a feeling of intoxication “High”, it does not cause addiction, dependence or the need for dose increase and its common side effects are almost imperceptible and usually disappear after use for a few days.
The CBD revolution exposes the versatile molecule to a public that has never heard of it. The selection of products, easy and convenient take-and-use bikes accelerate its spread to new markets every day. Over 80% of first-time users have expressed an interest in regular use of it but there are some risk groups that need to carefully check the possibility of self-care using CBD oil.
Who should pay close attention before using CBD?
People who are in a high-risk medical condition and are taking medications with serious side effects should consult a doctor before using CBD. CBD is a molecule with an extremely high level of safety and in the hundreds of thousands of studies carried out there (even on humans) no significant morbidity, addiction or side effects have been observed.
At the same time it is known that certain prescription drugs are metabolized by those worked enzymes that also break down the CBD and therefore it is recommended to check and consult the attending physician if there is no collision between the drug and CBD. In most cases, the drug can be replaced with a drug that does not break down by the same enzymes in the liver.
On our site you will find a guide to drug collisions and at the same time a list of medications that are not recommended to be taken in parallel with the CBD.
It is not just people who take prescription medications who should pay attention before choosing CBD products. Even people who are sensitive to a minimal amount of THC, the psychoactive molecule in the cannabis plant, will advise them to avoid CBD full spectrum products that contain the minimum amount of 0.3% THC and in their place experiment with pure organic CBD products (Isolate). Those who undergo drug testing should also refrain from using Full Spectrum CBD products because they contain a trace amount of THC molecule under the Dangerous Drugs Ordinance.
We do not in any way recommend taking cannabis by those who are not 18 by law. Studies of medicinal cannabis are inconclusive regarding its possible effects on the development of the brain and central nervous system on children who are still in the developmental stage of their bodies, while using cannabis.
Although CBD is not intoxicating, it is not true to say that it has no psychoactive effects. Taking CBD by minors should be carried out while consulting a doctor and with the sole responsibility of the parent. Parents who have made a decision in consultation with a doctor to treat their child or child with CBD oil:
- Choose a product with a CBD concentration of 10% or less.
- Avoid Full Spectrum products that also contain the THC leased molecule.
- Find in the vicinity of the child during the first few times of use of the product in order to examine the possibility of allergy or significant side effects.
Pregnant or lactating women
We do not in any way recommend taking CBD during pregnancy or during breastfeeding. Despite the CBD’s high “safety profile”, extensive studies have not yet been carried out on the subject and without denying any possibility of possible damage to the foetus – there is no need to take unnecessary risks.
Postpartum depression: Its soothing and anti-anxiety properties of CBD are one of the main reasons for the use of CBD products among the population. A decision to use CBD oil due to birth depression should take place in conjunction with the attending physician in case the mother is still breastfeeding.
Recently CBD has become common in the treatment of animals and especially in dogs that respond in general as humans to CBD. In most animals there is an endocannabinoid system that is responsible as in man for the balance between body and mind. The mechanisms of action of the CBD in animals are the same as the mechanisms of action of the person and therefore the effect of CBD on animals will be beneficial and desired mainly for animals with inflammation, joint pain and aging.
However, insufficient studies have yet been done on the effect of CBD on animals, the desired dose according to body weight, etc., and therefore any treatment of animals is required in consultation with a veterinarian.
It’s worth knowing that dog breeds are very sensitive to cannabinoids because of their genetic makeup. In case you decide to treat your dog with CBD oil:
- Choose a product with a CBD concentration not exceeding 10%.
- Don’t give your animal more than one or two drop in the first use of CBD so you can check for allergy reactions or significant side effects.
- Stay with the animal
Side Effects of CBD
It is useful to be aware of the possible side effects before putting CBD into our diary routine. Although the possible side effects are minimal, it is important to remember that the substance may affect everyone in a different way, and what happens to one will not necessarily happen to another, so it is important to start with a low dose which increases gradually. Here’s how to notice side effects, if any, and reduce the dose back if there are one or more of the following side effects:
Thirst or dry mouth A 2006 study found that cannabinoid receptors are also found in cells that secrete salivary fluid, so that when CBD affects Endo-cannabinoid System activity, salivary glands have difficulty forming saliva.
Decrease in blood pressure When taking CBD at high doses, there is a chance of a decrease in blood pressure. It is recommended to consult a doctor before consuming CBD oil in case of blood pressure problems or in combination with medications to regulate blood viscosity.
Drowsiness and provocation Because CBD consumption affects different people differently, arousal or drowsiness are possible side effects in the first few days of use of the product. In case CBD consumption causes drowsy, avoid running heavy equipment or driving, and it is recommended to reduce the dose to a level that does not cause drowsy in the middle of the day.
Is there a recommended daily dose or maximum amount of CBD per day?
As part of the FDA-approved safety tests for a CBD-based drug called Epidiolex, doses of 600–1200mg of pure CBD per day were given to children suffering from a rare epileptic syndrome called Drava syndrome. No significant side effects were observed at a dose of 600mg daily and no liver toxicity developed, marking an “overdose”. No significant side effects were observed at the dose of 1200mg, although some patients were found to have developed liver toxicity. In light of this finding, the FDA decided to recommend limiting the taking of CBD to 600 kg per day.
The British Ministry of Health has decided not to take more than 300mg of CBD per day until further in-depth studies are carried out on the subject. Based on our experience we believe that a dose of 200 kg to 600 kg per day is completely safe but is also an imaginary dose… Most CBD consumers take an average of between 20mg and 100mg of CBD per day.
As of January 3, 2021, a warning of possible harm to the fertility of the male reproductive system must appear on cannabis and CBD products. (Proposition 65). The warning refers to harm to fertility during use and not to permanent and irreversible harm. The warning is based on the fact that any cannabinoid directly linked to the Endo-cannabinoid System receptors CB1 and CB2 such as THC will have a negative effect (at least while it is in the bloodstream) – on male reproductive function, because the Endo-cannabinoid System has a modular supervisor role in the hypothalamus-pituitary axis in hpg cells, The hypothalamus, pituitary gland, Leydig cells as well as testicular cancer cells, can be found in cannabinoid receptors that can affect testosterone production at the same time – CBD is not directly linked to CB1 and CB2 receptors – so its effects are more positive to the male reproductive system than isolated THC.
How does CBD affect testosterone levels?
There is evidence to suggest that CBD can play a role in balancing testosterone levels (T). CBD slows down the production process of testosterone while it is in the bloodstream and at the same time limits its breakdown in the liver, when the CBD is washed out of the bloodstream and testosterone production returns to normal.
There has been no long-term damage to testosterone production by CBD as no comprehensive research has yet been carried out on the subject and consult your healthcare professional. Men planning a pregnancy with their partners should consider stopping marijuana use and its derivatives for the duration.
See more about:
- The Grace Period for Proposition 65 Cannabis and CBD Reproductive Harm Warning Expired On January 3 – Are Your Labels Compliant?
- Mechanism for inhibitory effect of cannabidiol on microsomal testosterone oxidation in male rat liver
- Marijuana, Phyto-cannabinoids, the Endo-Cannabinoid System, and male fertility
- Marijuana consumption affects the male reproductive health
- Marijuana smoking and markers of testicular function among men from a fertility centre